Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.51 |
| ▸ | HTR1D | P28221 | 4/20 | 0.51 |
| ▸ | HTR1B | P28222 | 4/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5218582 | 0.86 | HTR1A (0.50) | HTR1AHTR1DHTR1BSLC6A4PRKCQ | |
| Hydrochloric Acid SCHEMBL5218579 | 0.85 | HTR1A (0.49) | HTR1AHTR1DHTR1BSLC6A4PRKCQ | |
| SCHEMBL13164143 | 0.77 | HTT (0.48) | HTR1AHTR1DHTR1BSLC6A4HTT | |
| SCHEMBL4176340 | 0.75 | HTR1A (0.50) | HTR1AHTR1DHTR1BSLC6A4HTT | |
| SCHEMBL13927918 | 0.74 | HTR1A (0.45) | HTR1AHTR1DHTR1BSLC6A4PRKCQ | |
| SCHEMBL10208416 | 0.74 | CYP1A2 (0.49) | HTR1AHTR1DHTR1BSLC6A4HTT | |
| SCHEMBL16184461 | 0.73 | HTT (0.51) | HTR1AHTR1DHTR1BSLC6A4HTT | |
| SCHEMBL5986135 | 0.73 | TSHR (0.70) | HTTTSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13927924 | 0.73 | CTSC (0.47) | HTR1AHTR1DHTR1BSLC6A4PRKCQ | |
| SCHEMBL4186254 | 0.72 | PARP1 (0.60) | HTR1AHTR1DHTR1BSLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330460-A2 | BENZOXAZINONE DERIVATIVES, THEIR PREPARATION AND USE | SMITHKLINE BEECHAM PLC (GB) | 2003-07-30 | — | — | EP | disclosed |
| WO-2002034754-A2 | BENZOXAZINONE DERIVATIVES, THEIR PREPARATION AND USE | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-05-02 | — | — | WO | disclosed |