Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 5/20 | 0.85 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.85 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7162141 | 0.93 | OXTR (0.73) | OXTRAVPR1ACHRNA7AVPR2ADRB1 | |
| SCHEMBL5478504 | 0.92 | OXTR (0.72) | OXTRAVPR1ACHRNA7ADRB1ADRB3 | |
| SCHEMBL5478502 | 0.92 | OXTR (0.72) | OXTRAVPR1ACHRNA7ADRB1ADRB3 | |
| SCHEMBL4936354 | 0.92 | OXTR (1.00) | OXTRAVPR1AAVPR2ROCK2ROCK1 | |
| SCHEMBL4936174 | 0.92 | OXTR (1.00) | OXTRAVPR1AAVPR2ROCK2ROCK1 | |
| SCHEMBL4940385 | 0.92 | OXTR (1.00) | OXTRAVPR1AAVPR2ROCK2ROCK1 | |
| SCHEMBL4942975 | 0.92 | OXTR (1.00) | OXTRAVPR1AAVPR2ROCK2ROCK1 | |
| SCHEMBL4943198 | 0.92 | OXTR (1.00) | OXTRAVPR1AAVPR2ROCK2ROCK1 | |
| SCHEMBL5743785 | 0.92 | OXTR (1.00) | OXTRAVPR1AAVPR2ROCK2ROCK1 | |
| SCHEMBL5743780 | 0.92 | OXTR (1.00) | OXTRAVPR1AAVPR2ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212012-A1 | Pharmaceutically active pyrrolidine derivatives | MERCK SERONO SA (CH) | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212012-A1 | Pharmaceutically active pyrrolidine derivatives | OXTR, CNR1, PRLHR | OXTR 1/4885AVPR1A 203/4885CHRNA7 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.