SCHEMBL709252

SCHEMBL709252

C[C@H](N)C(=O)OC(=O)[C@H](C)N

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.36
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA4 P43681 1/20 0.34
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34
GRIN2B Q13224 1/20 0.34
GRIN2C Q14957 1/20 0.34
GRIN3A Q8TCU5 1/20 0.34
CYP3A4 P08684 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
NFKB1 P19838 1/20 0.33
CYP2C19 P33261 1/20 0.33
DPP4 P27487 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6536106 1.00 SLC7A5 (0.36) SLC7A5CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL2027762 1.00 SLC7A5 (0.36) SLC7A5CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL866414 1.00 SLC7A5 (0.36) SLC7A5CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL17222464 1.00 SLC7A5 (0.36) SLC7A5CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL4256725 0.91 TSHR (0.33) SLC7A5CHRNB2CHRNB4CHRNA3CHRNA4
Ethylene Glycol SCHEMBL15602746 0.89 CHRNB2 (0.34) SLC7A5CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL29397848 0.89 TP53 (0.36) SLC7A5CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL12273577 0.89 TP53 (0.36) SLC7A5CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL11452947 0.87 GRIN2D (0.30) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL10710883 0.87 SLC7A5 (0.46) SLC7A5GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023200842-A1 COMPOSITIONS AND METHODS FOR TREATING SOLID CANCER EXOXEMIS, INC. (US) 2023-10-19 WO claimed
EP-3463431-A1 MYELOPEROXIDASE COMPOSITIONS AND METHODS FOR INHIBITION OF LIPOPOLYSACCHARIDES AND LIPID A Exoxemis, Inc. (US) 2019-04-10 EP claimed
CN-109414485-A For inhibiting the myeloperoxidase enzymatic compositions and method of lipopolysaccharides and lipid A 埃欧艾米斯公司 2019-03-01 CN claimed
CN-106432676-B A kind of preparation method of N/P/ nanometers of synergistic extinguishing waterborn polyurethane dispersion liquid 齐鲁工业大学 2018-12-25 CN claimed
WO-2017204918-A1 MYELOPEROXIDASE COMPOSITIONS AND METHODS FOR INHIBITION OF LIPOPOLYSACCHARIDES AND LIPID A EXOXEMIS, INC. (US) 2017-11-30 WO claimed
CN-106432676-A Preparation method of N/P/nano synergistic flame-retardant waterborne polyurethane dispersion liquid 齐鲁工业大学 2017-02-22 CN claimed
EP-2731601-A2 EOSINOPHIL PEROXIDASE COMPOSITIONS AND METHODS OF THEIR USE Exoxemis, Inc. (US) 2014-05-21 EP claimed
WO-2013009910-A2 EOSINOPHIL PEROXIDASE COMPOSITIONS AND METHODS OF THEIR USE EXOXEMIS, INC. (US) 2013-01-17 WO claimed
CN-102014950-A Compositions for enhancing the antibacterial activity of myeloperoxidase and methods of use thereof EXOXEMIS INC 2011-04-13 CN claimed
EP-2296693-A1 COMPOSITIONS FOR ENHANCING THE ANTIBACTERIAL ACTIVITY OF MYELOPEROXIDASE AND METHODS OF USE THEREOF Exoxemis, Inc. (US) 2011-03-23 EP claimed
WO-2009137697-A1 COMPOSITIONS FOR ENHANCING THE ANTIBACTERIAL ACTIVITY OF MYELOPEROXIDASE AND METHODS OF USE THEREOF EXOXEMIS, INC. (US) 2009-11-12 WO claimed
CN-1325063-C L-amino acid water-soluble pearl powder and its preparing method SONG TINGSHENG (CN) 2007-07-11 CN claimed
CN-1709282-A L-amino acid water-soluble pearl powder and its preparing method SONG TINGSHENG (CN) 2005-12-21 CN claimed
EP-0199432-B1 ASSAYING METHOD FOR PRIMARY AMINES USING AROMATIC DIALDEHYDES OREAD LABORATORIES, INC. (US) 1991-05-29 EP claimed
JP-58116683-A None JP disclosed
US-12636312-B2 Gold clusters (AuCs), composition and method for treatment of liver cirrhosis WUHAN VAST CONDUCT SCIENCE FOUNDATION CO., LTD. (CN) 2026-05-26 US disclosed
US-20250325635-A1 MODIFIED VASOACTIVE INTESTINAL PEPTIDES IMMUNOFORGE CO LTD (KR) 2025-10-23 US disclosed
US-4382081-A ANTIARRTHRITIC AGENTS E. R. SQUIBB & SONS, INC. (US) 1983-05-03 US disclosed
US-4312885-A ANORECTIC AGENTS FOR TREATMENT OF OBESITY HOFFMANN-LA ROCHE INC. (US) 1982-01-26 US disclosed
US-4084980-A STABILIZERS OF ACTIVATED CARBON, ZEOLITE, SILICA GEL, CARBON BLACK, TALC, AND MICA SHIKOKU KAKEN KOGYO KABUSHIKI KAISHA (JA) 1978-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12636312-B2 Gold clusters (AuCs), composition and method for treatment of liver cirrhosis FABP1, ALB, CSTB SLC7A5 104/4885CHRNB2 2380/4885CHRNB4 2880/4885
US-20250325635-A1 MODIFIED VASOACTIVE INTESTINAL PEPTIDES VIP, VIPR1, VIPR2 SLC7A5 776/4885CHRNB2 314/4885CHRNB4 237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.