Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 3/20 | 0.32 |
| ▸ | USP10 | Q14694 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7092531 | 1.00 | SERPINE1 (0.37) | SERPINE1SYKHDAC3HDAC4HDAC1 | |
| SCHEMBL8362207 | 0.87 | SERPINE1 (0.37) | SERPINE1SYKHDAC3HDAC4HDAC1 | |
| SCHEMBL7001569 | 0.87 | SERPINE1 (0.37) | SERPINE1SYKHDAC3HDAC4HDAC1 | |
| SCHEMBL7001565 | 0.87 | SERPINE1 (0.37) | SERPINE1SYKHDAC3HDAC4HDAC1 | |
| SCHEMBL6986607 | 0.85 | SERPINE1 (0.37) | SERPINE1SYKHDAC3HDAC4HDAC1 | |
| SCHEMBL6996062 | 0.85 | SERPINE1 (0.37) | SERPINE1SYKHDAC3HDAC4HDAC1 | |
| SCHEMBL6986606 | 0.85 | SERPINE1 (0.37) | SERPINE1SYKHDAC3HDAC4HDAC1 | |
| SCHEMBL6998895 | 0.84 | SERPINE1 (0.38) | SERPINE1SYKHDAC3HDAC4HDAC1 | |
| SCHEMBL7000933 | 0.84 | SERPINE1 (0.38) | SERPINE1SYKHDAC3HDAC4HDAC1 | |
| SCHEMBL6998902 | 0.84 | SERPINE1 (0.38) | SERPINE1SYKHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846111-B1 | SYNTHESES OF OPTICALLY PURE COMPOUNDS USEFUL AS GARFT INHIBITORS AND THEIR INTERMEDIATES | AGOURON PHARMA (US) | 2003-08-27 | — | — | EP | disclosed |