Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 10/20 | 0.41 |
| ▸ | MPC2 | O95563 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6186454 | 1.00 | FFAR1 (0.47) | FFAR1MAPTPPARGMPC2CYP2C8 | |
| SCHEMBL6182414 | 1.00 | FFAR1 (0.47) | FFAR1MAPTPPARGMPC2CYP2C8 | |
| SCHEMBL5568294 | 0.86 | FFAR1 (0.45) | FFAR1MAPTPPARGMPC2CYP2C8 | |
| SCHEMBL6182509 | 0.86 | FFAR1 (0.51) | FFAR1 | |
| SCHEMBL6183069 | 0.86 | FFAR1 (0.51) | FFAR1 | |
| SCHEMBL6184372 | 0.86 | FFAR1 (0.51) | FFAR1 | |
| SCHEMBL6183217 | 0.86 | FFAR1 (0.51) | FFAR1 | |
| SCHEMBL6987927 | 0.86 | FFAR1 (0.51) | FFAR1 | |
| SCHEMBL6182641 | 0.85 | FFAR1 (0.55) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6183077 | 0.85 | FFAR1 (0.52) | FFAR1MAPTPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309575-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | Galderma Research & Development (FR) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002012210-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2002-02-14 | — | — | WO | disclosed |