Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenanthridine SCHEMBL30914262 | 0.88 | GPR3 (1.00) | GPR3KDM4ECYP3A4TOP2AMEN1 | |
| Phenanthridine SCHEMBL9106884 | 0.88 | GPR3 (1.00) | GPR3KDM4ECYP3A4TOP2AMEN1 | |
| Phenanthridine SCHEMBL30823553 | 0.88 | GPR3 (1.00) | GPR3KDM4ECYP3A4TOP2AMEN1 | |
| Phenanthridine SCHEMBL8666 | 0.88 | GPR3 (1.00) | GPR3KDM4ECYP3A4TOP2AMEN1 | |
| Phenanthridine SCHEMBL29087045 | 0.86 | GPR3 (0.87) | GPR3KDM4ECYP3A4TOP2AMEN1 | |
| Phenanthridine SCHEMBL23003530 | 0.86 | GPR3 (0.95) | GPR3KDM4ECYP3A4TOP2AMEN1 | |
| Phenanthridine SCHEMBL3702845 | 0.86 | GPR3 (0.95) | GPR3KDM4ECYP3A4TOP2AMEN1 | |
| Phenanthridine SCHEMBL460289 | 0.86 | GPR3 (0.95) | GPR3KDM4ECYP3A4TOP2AMEN1 | |
| Phenanthridine SCHEMBL2422346 | 0.86 | GPR3 (0.95) | GPR3KDM4ECYP3A4TOP2AMEN1 | |
| Phenanthridine SCHEMBL8505090 | 0.86 | GPR3 (0.95) | GPR3KDM4ECYP3A4TOP2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334115-A1 | PHENANTHRIDINE DERIVATIVES AND ANTITUMORAL MEDICAMENTS CONTAINING PHENANTHRIDINE | Clement, Bernd (DE) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002036607-A1 | PHENANTHRIDINE DERIVATIVES AND ANTITUMORAL MEDICAMENTS CONTAINING PHENANTHRIDINE | CLEMENT BERND (DE) | 2002-05-10 | — | — | WO | disclosed |
| US-4108667-A | Photographic compositions and elements containing benzo[a]quinolizinium methine dyes | EASTMAN KODAK COMPANY (US) | 1978-08-22 | — | — | US | disclosed |