Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7092866 | 0.88 | ACHE (0.42) | F10GAAKDM2BMAPTLMNA | |
| SCHEMBL7097521 | 0.84 | F10 (0.42) | F10CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7098239 | 0.82 | F10 (0.42) | F10GAAMAPTLMNATHRB | |
| SCHEMBL7092545 | 0.81 | MAPT (0.42) | F10GAAMAPTLMNATHRB | |
| SCHEMBL7139465 | 0.79 | MAPT (0.40) | F10GAAMAPTLMNATHRB | |
| SCHEMBL6424181 | 0.77 | F10 (0.39) | F10GAAKDM2BMAPTLMNA | |
| SCHEMBL7092571 | 0.73 | F10 (0.42) | F10MAPT | |
| Hydrochloric Acid SCHEMBL6420510 | 0.73 | F10 (0.43) | F10GAAMAPTLMNATHRB | |
| SCHEMBL6421346 | 0.72 | MAPT (0.40) | F10GAAMAPTLMNATHRB | |
| SCHEMBL7098081 | 0.71 | ACHE (0.41) | GAAMAPTLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289953-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096304-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |