Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27395742 | 0.77 | ALDH1A1 (0.67) | METAP2BCAT2ALDH1A1MAPTKDM4E | |
| Carbamic Acid SCHEMBL28336611 | 0.75 | ALDH1A1 (0.64) | METAP2BCAT2ALDH1A1MAPTKDM4E | |
| SCHEMBL39118 | 0.74 | ALDH1A1 (0.70) | METAP2BCAT2ALDH1A1MAPTKDM4E | |
| SCHEMBL27700719 | 0.74 | ALDH1A1 (0.70) | METAP2BCAT2ALDH1A1MAPTKDM4E | |
| SCHEMBL4967588 | 0.74 | ALDH1A1 (0.70) | METAP2BCAT2ALDH1A1MAPTKDM4E | |
| SCHEMBL3644388 | 0.74 | NPSR1 (0.47) | NPSR1METAP2BCAT2ALDH1A1MAPT | |
| Potassium SCHEMBL317509 | 0.72 | ALDH1A1 (0.67) | METAP2BCAT2ALDH1A1MAPTKDM4E | |
| SCHEMBL1158413 | 0.72 | ALDH1A1 (0.67) | METAP2BCAT2ALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL8612216 | 0.72 | ALDH1A1 (0.67) | METAP2BCAT2ALDH1A1MAPTKDM4E | |
| SCHEMBL31285706 | 0.72 | ALDH1A1 (0.67) | METAP2BCAT2ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | claimed |
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | disclosed |