Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10594597 | 1.00 | LMNA (0.55) | LMNAGLO1TDP1CYP2D6ALDH1A1 | |
| SCHEMBL10594600 | 1.00 | LMNA (0.55) | LMNAGLO1TDP1CYP2D6ALDH1A1 | |
| SCHEMBL7093404 | 1.00 | LMNA (0.55) | LMNAGLO1TDP1CYP2D6ALDH1A1 | |
| SCHEMBL10594599 | 1.00 | LMNA (0.55) | LMNAGLO1TDP1CYP2D6ALDH1A1 | |
| SCHEMBL10594613 | 1.00 | LMNA (0.55) | LMNAGLO1TDP1CYP2D6ALDH1A1 | |
| SCHEMBL7093406 | 1.00 | LMNA (0.55) | LMNAGLO1TDP1CYP2D6ALDH1A1 | |
| SCHEMBL10594606 | 1.00 | LMNA (0.55) | LMNAGLO1TDP1CYP2D6ALDH1A1 | |
| SCHEMBL10561807 | 0.86 | LMNA (0.50) | LMNAGLO1TDP1CYP2D6ALDH1A1 | |
| SCHEMBL10561797 | 0.86 | LMNA (0.50) | LMNAGLO1TDP1CYP2D6ALDH1A1 | |
| SCHEMBL10563981 | 0.86 | LMNA (0.50) | LMNAGLO1TDP1CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1018503-B1 | Process of producing cyclopropanecarboxylate compounds | SUMITOMO CHEMICAL CO (JP) | 2003-08-13 | — | — | EP | disclosed |
| US-6414181-B1 | REACTING CYCLOPROPANECARBALDEHYDE COMPOUND WITH DICARBOXYLATE COMPOUND IN PRESENCE OF AT LEAST ONE SECONDARY AMINE CHOOSEN FROM PIPERIDINE, MORPHOLINE, PYRROLIDINE, DIETHYLAMINE AND N-METHYLETHANOLAMINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-1018503-A1 | Process of producing cyclopropanecarboxylate compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-07-12 | — | — | EP | disclosed |