Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 17/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14345234 | 1.00 | MAOA (0.53) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL5231053 | 1.00 | MAOA (0.53) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL5229456 | 0.90 | MAOA (0.63) | MAOAMAOBCYP3A4CYP2D6 | |
| SCHEMBL5232889 | 0.89 | MAOA (0.53) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL4017272 | 0.86 | MAOA (0.51) | MAOAMAOBKCNH2 | |
| SCHEMBL5236005 | 0.86 | MAOA (0.38) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL5237085 | 0.85 | MAOA (0.50) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL27591382 | 0.83 | MAOA (0.37) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL5234209 | 0.82 | MAOA (0.60) | MAOAMAOBCYP3A4CYP2D6 | |
| SCHEMBL5233346 | 0.82 | MAOA (0.35) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286998-A1 | OXAZOLIDINONE DERIVATIVES WITH ANTIBIOTIC ACTIVITY | AstraZeneca AB (SE) | 2003-03-05 | — | — | EP | claimed |
| WO-2001081350-A1 | OXAZOLIDINONE DERIVATIVES WITH ANTIBIOTIC ACTIVITY | ASTRAZENECA AB (SE) | 2001-11-01 | — | — | WO | claimed |