Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 2/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672446 | 0.92 | KCNH2 (0.45) | KCNH2TOP1 | |
| SCHEMBL7093170 | 0.91 | KCNH2 (0.38) | KCNH2POLBTOP1TYMP | |
| SCHEMBL6668975 | 0.90 | KCNH2 (0.38) | KCNH2POLBTOP1TYMP | |
| SCHEMBL6669775 | 0.89 | KCNH2 (0.33) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL6669192 | 0.88 | KCNH2 (0.33) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL7093861 | 0.88 | KCNH2 (0.35) | KCNH2 | |
| SCHEMBL6669319 | 0.88 | KCNH2 (0.32) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL6668519 | 0.87 | KCNH2 (0.38) | KCNH2POLBTOP1TYMP | |
| SCHEMBL6644192 | 0.87 | KCNH2 (0.33) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL6642661 | 0.87 | TOP1 (0.34) | KCNH2CACNA1FPOLBMAPK1CACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030114666-A1 | Having quinazolindione core structure; non-antibiotic resistance | WARNER-LAMBERT COMPANY | 2003-06-19 | — | — | US | claimed |
| US-20030114666-A1 | Having quinazolindione core structure; non-antibiotic resistance | WARNER-LAMBERT COMPANY | 2003-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114666-A1 | Having quinazolindione core structure; non-antibiotic resistance | ABCC1, RPS6KA1, SIGMAR1 | KCNH2 143/4885CACNA1F 2279/4885POLB 3318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.