Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 10/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 4/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL72704 | 0.88 | SCD (0.46) | SCDEPHX2CCR2 | |
| SCHEMBL29385267 | 0.88 | SCD (0.47) | SCDEPHX2CCR2 | |
| SCHEMBL70152 | 0.88 | EPHX2 (0.46) | SCDEPHX2CCR2 | |
| SCHEMBL29385279 | 0.88 | EPHX2 (0.46) | SCDEPHX2CCR2 | |
| SCHEMBL29382110 | 0.88 | EPHX2 (0.46) | SCDEPHX2CCR2 | |
| SCHEMBL69854 | 0.88 | SCD (0.47) | SCDEPHX2CCR2 | |
| SCHEMBL70856 | 0.88 | EPHX2 (0.46) | SCDEPHX2CCR2 | |
| SCHEMBL68443 | 0.87 | EPHX2 (0.49) | SCDEPHX2CCR2 | |
| SCHEMBL29382083 | 0.87 | EPHX2 (0.49) | SCDEPHX2CCR2 | |
| SCHEMBL70227 | 0.85 | SCD (0.55) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268143-A2 | NOVEL PIPERIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | Forest Laboratories Holdings Limited (BM) | 2011-01-05 | — | — | EP | disclosed |