Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 5/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70937 | 0.88 | SCD (0.47) | SCDEPHX2CCR2 | |
| SCHEMBL29382368 | 0.87 | EPHX2 (0.46) | SCDEPHX2ALDH1A1HPGDSCD5 | |
| SCHEMBL29385132 | 0.87 | EPHX2 (0.46) | SCDEPHX2SCD5RAB9ACCR2 | |
| SCHEMBL70288 | 0.87 | EPHX2 (0.46) | SCDEPHX2ALDH1A1HPGDSCD5 | |
| SCHEMBL68582 | 0.87 | EPHX2 (0.46) | SCDEPHX2SCD5RAB9ACCR2 | |
| SCHEMBL69757 | 0.86 | SCD5 (0.57) | SCDEPHX2HPGDSCD5RAB9A | |
| SCHEMBL29384989 | 0.86 | SCD5 (0.57) | SCDEPHX2HPGDSCD5RAB9A | |
| SCHEMBL68819 | 0.84 | SCD (0.53) | SCDALDH1A1HPGDKDM4ENPSR1 | |
| SCHEMBL70077 | 0.83 | SCD5 (0.49) | SCDEPHX2ALDH1A1KDM4ESCD5 | |
| SCHEMBL29384505 | 0.83 | SCD5 (0.49) | SCDEPHX2ALDH1A1KDM4ESCD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268143-A2 | NOVEL PIPERIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | Forest Laboratories Holdings Limited (BM) | 2011-01-05 | — | — | EP | disclosed |