SCHEMBL7093707

SCHEMBL7093707

CCc1nc(Nc2ccc(F)cc2C)nc(N2CCc3ccsc3C2C)c1C

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GALR2 O43603 1/20 0.31
HTT P42858 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6994945 0.99 GALR2 (0.31) GALR2
SCHEMBL7092841 0.89 GALR2 (0.33) GALR2HTT
Hydrochloric Acid SCHEMBL6991900 0.89 GALR2 (0.33) GALR2HTT
SCHEMBL6999239 0.84 AXL (0.33) GALR2
Hydrochloric Acid SCHEMBL6993574 0.83 AXL (0.33) GALR2
SCHEMBL7093465 0.81 GALR2 (0.37) GALR2HTT
Hydrochloric Acid SCHEMBL6995471 0.80 GALR2 (0.36) GALR2HTT
Hydrochloric Acid SCHEMBL8566459 0.77 RXFP1 (0.34) HTT
SCHEMBL7000866 0.76
Hydrochloric Acid SCHEMBL8565839 0.76 POLB (0.42) GALR2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0775120-B1 NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2003-06-04 EP claimed
CN-1110740-C Multi-key co-impact Chinese character coding input method and keyboard LUO KANGYI (CN) 2003-06-04 CN claimed
CN-1102144-C Noval pyrimidine derivatives and prepn. processes thereof YUHAN CORP (KR) 2003-02-26 CN claimed
CN-1155281-A Noval pyrimidine derivatives and prepn. processes thereof YUHAN CORP (KR) 1997-07-23 CN claimed
CN-1102144-C Noval pyrimidine derivatives and prepn. processes thereof YUHAN CORP (KR) 2003-02-26 CN disclosed