Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PRKDC | P78527 | 1/20 | 0.30 |
| ▸ | SCD | O00767 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6991900 | 0.99 | GALR2 (0.33) | GALR2HTTKDM4EALDH1A1PKM | |
| SCHEMBL7093707 | 0.89 | GALR2 (0.31) | GALR2HTT | |
| Hydrochloric Acid SCHEMBL6994945 | 0.89 | GALR2 (0.31) | GALR2 | |
| SCHEMBL7825640 | 0.85 | GALR2 (0.35) | GALR2HTTKDM4EALDH1A1AXL | |
| SCHEMBL7093465 | 0.84 | GALR2 (0.37) | GALR2HTTRXFP1PIK3CAPRKDC | |
| Hydrochloric Acid SCHEMBL6158437 | 0.84 | GALR2 (0.34) | GALR2HTTKDM4EALDH1A1AXL | |
| Hydrochloric Acid SCHEMBL6161429 | 0.84 | GALR2 (0.34) | GALR2HTTKDM4EALDH1A1AXL | |
| Hydrochloric Acid SCHEMBL8566459 | 0.83 | RXFP1 (0.34) | HTTPKMRXFP1 | |
| Hydrochloric Acid SCHEMBL6995471 | 0.83 | GALR2 (0.36) | GALR2HTTRXFP1PIK3CAPRKDC | |
| SCHEMBL6997579 | 0.83 | AXL (0.35) | GALR2HTTKDM4EALDH1A1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775120-B1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2003-06-04 | — | — | EP | claimed |