Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 2/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | IAPP | P10997 | 3/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL465035 | 0.95 | CNR1 (0.53) | CNR1CNR2CDK1TYRTRIM24 | |
| SCHEMBL1527080 | 0.91 | TRPA1 (0.57) | TRPA1CDK1TYRTRIM24TRIM33 | |
| SCHEMBL7094408 | 0.87 | CDK1 (0.65) | CNR1CNR2TRPA1CDK1IAPP | |
| SCHEMBL1527086 | 0.85 | CDK1 (0.57) | CDK1TYRTRIM24TRIM33IAPP | |
| SCHEMBL21002110 | 0.84 | CDK1 (0.58) | CDK1TYRTRIM24TRIM33BACE1 | |
| SCHEMBL1527136 | 0.83 | CDK1 (0.60) | CDK1IAPPCYP3A4HIF1AHSD17B10 | |
| SCHEMBL28823310 | 0.82 | CDK1 (0.63) | CDK1CYP3A4HIF1AHSD17B10 | |
| SCHEMBL29189689 | 0.82 | CDK1 (0.63) | CDK1CYP3A4HIF1AHSD17B10 | |
| SCHEMBL28970004 | 0.82 | CDK1 (0.63) | CDK1CYP3A4HIF1AHSD17B10 | |
| SCHEMBL10803882 | 0.82 | CDK1 (0.63) | CDK1CYP3A4HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334107-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | Basell Polyolefine GmbH (DE) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002032908-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2002-04-25 | — | — | WO | disclosed |