Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9240088 | 0.98 | BCL2L1 (0.42) | BCL2L1BADPRNPRXFP1KDM4E | |
| SCHEMBL10416253 | 0.98 | BCL2L1 (0.42) | BCL2L1BADPRNPRXFP1KDM4E | |
| SCHEMBL10695816 | 0.89 | KMT2A (0.44) | KDM4EMEN1KMT2AMETAP2PLAU | |
| SCHEMBL29496067 | 0.79 | PRNP (0.58) | PRNPRXFP1ALDH1A1NPC1ACHE | |
| SCHEMBL3792562 | 0.79 | PRNP (0.42) | PRNPRXFP1KDM4EKMT2AALDH1A1 | |
| SCHEMBL15886676 | 0.79 | PRNP (0.52) | PRNPRXFP1KDM4EALDH1A1NPC1 | |
| SCHEMBL19618086 | 0.77 | PIM1 (0.47) | KDM4EMEN1KMT2AMETAP2PLAU | |
| SCHEMBL29496040 | 0.76 | RXFP1 (0.63) | PRNPRXFP1KDM4EALDH1A1NPC1 | |
| SCHEMBL9559130 | 0.76 | NPC1 (0.43) | PRNPRXFP1KDM4EALDH1A1NPC1 | |
| SCHEMBL9406712 | 0.76 | RXFP1 (0.40) | PRNPRXFP1KDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1280771-A2 | NOVEL PRODRUGS VON 6-HYDROXY-2,3-DIHYDRO-1H-INDOLES, 5-HYDROXY-1,2-DIHYDRO-3H-PYRROLO 3,2-E]INDOLES AND 5-HYDROXY-1,2-DIHYDRO-3H-BENZO(E)INDOLES AS WELL AS OF 6-HYDROXY-1,2,3,4-TETRAHYDRO-BENZO F]QUINOLINE DERIVATIVES FOR USE IN SELECTIVE CANCER THERAPY | Tietze, Lutz F., Prof. Dr. (DE) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001083448-A2 | NOVEL PRODRUGS VON 6-HYDROXY-2,3-DIHYDRO-1H-INDOLES, 5-HYDROXY-1,2-DIHYDRO-3H-PYRROLO[3,2-E]INDOLES AND 5-HYDROXY-1,2-DIHYDRO-3H-BENZO(E)INDOLES AS WELL AS OF 6-HYDROXY-1,2,3,4-TETRAHYDRO-BENZO[F]QUINOLINE DERIVATIVES FOR USE IN SELECTIVE CANCER THERAPY | TIETZE LUTZ F (DE) | 2001-11-08 | — | — | WO | disclosed |
| US-5468825-A | Coating composition for carriers for use in electrophotography and carriers using the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-11-21 | — | — | US | disclosed |