Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | METAP2 | P50579 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | COMT | P21964 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093937 | 0.89 | BCL2L1 (0.43) | KMT2AMEN1KDM4EMETAP2PLAU | |
| SCHEMBL10416253 | 0.88 | BCL2L1 (0.42) | KMT2AMEN1KDM4EMETAP2PLAU | |
| SCHEMBL9240088 | 0.88 | BCL2L1 (0.42) | KMT2AMEN1KDM4EMETAP2PLAU | |
| SCHEMBL19618086 | 0.83 | PIM1 (0.47) | KMT2AMEN1KDM4EMETAP2PLAU | |
| SCHEMBL3246323 | 0.75 | METAP2 (0.56) | KMT2AMEN1KDM4EMETAP2PLAU | |
| SCHEMBL19618898 | 0.72 | MEN1 (0.44) | KMT2AMEN1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL14610638 | 0.71 | METAP2 (0.57) | KMT2AMEN1KDM4EMETAP2PLAU | |
| SCHEMBL10529134 | 0.70 | KDM4E (0.50) | KMT2AMEN1KDM4EMETAP2PLAU | |
| SCHEMBL28981243 | 0.68 | ALDH1A1 (0.52) | KMT2AMEN1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL6005307 | 0.68 | KMT2A (0.49) | KMT2AMEN1KDM4EMETAP2PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4772658-A | ADDITION POLYMERIZATION, POLYISOCYANATE-UNSATURATED ALCOHOL ADDUCT, POLYURETHANES, MOLDINGS | THE DOW CHEMICAL COMPANY (US) | 1988-09-20 | — | — | US | disclosed |