Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | MPL | P40238 | 2/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1527086 | 0.87 | CDK1 (0.57) | CDK1PPARANPC1HPGDMAPK1 | |
| SCHEMBL7091136 | 0.87 | CDK1 (0.60) | TRPV1CDK1RARBMCL1KAT8 | |
| SCHEMBL1527136 | 0.83 | CDK1 (0.60) | CDK1PPARANPC1HPGDMAPK1 | |
| SCHEMBL10803882 | 0.82 | CDK1 (0.63) | CDK1PPARAKAT8 | |
| SCHEMBL28970004 | 0.82 | CDK1 (0.63) | CDK1PPARAKAT8 | |
| SCHEMBL28823310 | 0.82 | CDK1 (0.63) | CDK1PPARAKAT8 | |
| SCHEMBL29189689 | 0.82 | CDK1 (0.63) | CDK1PPARAKAT8 | |
| SCHEMBL29398976 | 0.81 | ALOX5 (0.57) | HPGDHTTALOX15MCL1 | |
| SCHEMBL2786991 | 0.81 | ALOX5 (0.57) | HPGDHTTALOX15MCL1 | |
| SCHEMBL9652705 | 0.79 | PSMB5 (0.60) | TRPV1CDK1PSMB5DHODHRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334107-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | Basell Polyolefine GmbH (DE) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002032908-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2002-04-25 | — | — | WO | disclosed |