Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 15/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094430 | 1.00 | PDE7A (0.41) | PDE7APDE4BDPP4L3MBTL1PDE7B | |
| SCHEMBL7016000 | 0.87 | PDE7A (0.40) | PDE7APDE4BL3MBTL1PDE7BALDH1A1 | |
| SCHEMBL7015998 | 0.87 | PDE7A (0.40) | PDE7APDE4BL3MBTL1PDE7BALDH1A1 | |
| SCHEMBL7097767 | 0.77 | PDE7A (0.40) | PDE7APDE4BL3MBTL1PDE7BALDH1A1 | |
| SCHEMBL7097766 | 0.77 | PDE7A (0.40) | PDE7APDE4BL3MBTL1PDE7BALDH1A1 | |
| SCHEMBL6795854 | 0.68 | ALDH1A1 (0.40) | ALDH1A1HPGDKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL7097210 | 0.68 | PDE7A (0.39) | PDE7APDE4BL3MBTL1PDE7BALDH1A1 | |
| SCHEMBL7097211 | 0.68 | PDE7A (0.39) | PDE7APDE4BL3MBTL1PDE7BALDH1A1 | |
| SCHEMBL6804689 | 0.65 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1HPGDKDM4ETSHR | |
| SCHEMBL29354937 | 0.63 | KMT2A (0.56) | PDE7APDE4BL3MBTL1PDE7BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003089441-A1 | TRICYCLIC MERCAPTANS, METHOD FOR THEIR PRODUCTION AND THE USE THEREOF AS MMP INHIBITORS | IBFB GMBH (DE) | 2003-10-30 | — | — | WO | claimed |
| WO-2003089441-A1 | TRICYCLIC MERCAPTANS, METHOD FOR THEIR PRODUCTION AND THE USE THEREOF AS MMP INHIBITORS | IBFB GMBH (DE) | 2003-10-30 | — | — | WO | disclosed |