Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | PRKCB | P05771 | 1/20 | 0.32 |
| ▸ | PRKCH | P24723 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.31 |
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094498 | 1.00 | PRKCA (0.32) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL7094794 | 0.91 | CNR1 (0.30) | CNR1DAGLA | |
| SCHEMBL7094793 | 0.91 | CNR1 (0.30) | CNR1DAGLA | |
| SCHEMBL3803247 | 0.89 | PRKCA (0.32) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL1120169 | 0.89 | PRKCA (0.32) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL3313686 | 0.89 | PRKCA (0.32) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL724545 | 0.89 | PRKCA (0.32) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL7099016 | 0.85 | DAGLA (0.33) | DAGLA | |
| SCHEMBL7099012 | 0.85 | DAGLA (0.33) | DAGLA | |
| SCHEMBL7095131 | 0.81 | PRKCA (0.30) | PRKCAPRKD3PRKCGPRKCBPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003088975-A1 | INHIBITION OF FATTY ACID SYNTHASE BY BETA-LACTONES AND OTHER COMPOUNDS FOR INHIBITION OF CELLULAR PROLIFERATION | THE BURNHAM INSTITUTE (US) | 2003-10-30 | — | — | WO | disclosed |