Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 17/20 | 0.71 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morphanthridine SCHEMBL1150250 | 0.80 | TRPA1 (1.00) | TRPA1 | |
| Morphanthridine SCHEMBL1509656 | 0.78 | TRPA1 (0.96) | TRPA1 | |
| SCHEMBL28854449 | 0.74 | TRPA1 (0.46) | TRPA1HTR2CTDP1L3MBTL1 | |
| SCHEMBL13098180 | 0.71 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL18350153 | 0.69 | TRPA1 (0.52) | TRPA1SLC6A2HTR2AHTR2CSLC6A4 | |
| SCHEMBL23233885 | 0.69 | — | — | |
| SCHEMBL563921 | 0.69 | TRPA1 (0.57) | TRPA1SLC6A2HTR2AHTR2CSLC6A4 | |
| SCHEMBL31145655 | 0.69 | TRPA1 (0.70) | TRPA1 | |
| SCHEMBL8381353 | 0.67 | TRPA1 (0.68) | TRPA1 | |
| SCHEMBL7456203 | 0.67 | TRPA1 (0.43) | TRPA1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910563-B1 | INTEGRIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6008213-A | A INHIBITOR OF VITRONECTIN RECEPTOR AND FIBRINOGEN RECEPTOR; USEFUL FOR INHIBITING PLATELET AGGREGATION AND OSTEOPOROSIS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-12-28 | — | — | US | disclosed |