Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10365698 | 0.82 | SLC6A4 (0.58) | MEN1KMT2ASLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5672472 | 0.76 | KDM4E (0.51) | KDM4EMEN1KMT2ATSHRMCL1 | |
| SCHEMBL598212 | 0.75 | TDP1 (0.55) | TSHRSLC6A4SLC6A3SLC6A2ANPEP | |
| SCHEMBL30146580 | 0.73 | TDP1 (0.52) | TSHRSLC6A4SLC6A3SLC6A2ANPEP | |
| SCHEMBL30146557 | 0.73 | TDP1 (0.52) | TSHRSLC6A4SLC6A3SLC6A2ANPEP | |
| SCHEMBL4799370 | 0.73 | MMP2 (0.55) | TSHRSLC6A4SLC6A3SLC6A2ANPEP | |
| SCHEMBL7268763 | 0.73 | TDP1 (0.52) | TSHRSLC6A4SLC6A3SLC6A2ANPEP | |
| SCHEMBL10600089 | 0.73 | ABCB1 (0.62) | KDM4EMEN1KMT2ATSHRSIGMAR1 | |
| SCHEMBL11390977 | 0.72 | HSD17B2 (0.49) | KDM4EMEN1KMT2ATSHRHSD17B2 | |
| SCHEMBL583721 | 0.72 | CYP1A2 (0.58) | MEN1KMT2ATSHRSLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003089476-A1 | CROSS-LINKED HYALURONATE COMPOUNDS | GENZYME CORPORATION (US) | 2003-10-30 | — | — | WO | claimed |
| WO-2003089476-A1 | CROSS-LINKED HYALURONATE COMPOUNDS | GENZYME CORPORATION (US) | 2003-10-30 | — | — | WO | disclosed |
| WO-2003089026-A1 | AZIRIDINE COMPOUNDS AND THEIR USE IN MEDICAL DEVICES | GENZYME CORPORATION (US) | 2003-10-30 | — | — | WO | disclosed |