Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.77 |
| ▸ | HRH1 | P35367 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 5/20 | 0.59 |
| ▸ | MAOB | P27338 | 5/20 | 0.59 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15897912 | 0.99 | HRH3 (0.74) | HRH3HRH1MAOAMAOB | |
| Hydrochloric Acid SCHEMBL6109241 | 0.88 | HRH3 (0.85) | HRH3HRH1MAOAMAOBPSMB1 | |
| Hydrochloric Acid SCHEMBL6110285 | 0.86 | HRH3 (0.97) | HRH3HRH1MAOAMAOB | |
| Hydrochloric Acid SCHEMBL6110579 | 0.86 | HRH3 (0.97) | HRH3HRH1MAOAMAOB | |
| SCHEMBL6150354 | 0.83 | HRH3 (1.00) | HRH3HRH1MAOAMAOB | |
| SCHEMBL6675509 | 0.82 | HRH3 (1.00) | HRH3HRH1 | |
| Hydrochloric Acid SCHEMBL6109604 | 0.82 | HRH3 (0.97) | HRH3HRH1MAOAMAOB | |
| SCHEMBL29923696 | 0.81 | MAOA (0.88) | HRH3MAOAMAOB | |
| SCHEMBL28841209 | 0.81 | MAOA (0.88) | HRH3MAOAMAOB | |
| SCHEMBL14287582 | 0.80 | HRH3 (0.88) | HRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309551-A1 | INDOLINE DERIVATIVES AS 5HT2C ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002014273-A1 | INDOLINE DERIVATIVES AS 5HT2C ANTAGONISTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-02-21 | — | — | WO | disclosed |