Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 5/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | HMGCR | P04035 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | CTH | P32929 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3080172 | 0.84 | HPGD (0.43) | ALDH1A1MAPTTDP1LMNAPTGS2 | |
| SCHEMBL20734738 | 0.81 | ECE1 (0.48) | MAPTFAAHADRA1AMEN1KMT2A | |
| SCHEMBL12942755 | 0.80 | HPGD (0.41) | ALDH1A1MAPTTDP1LMNAPTGS2 | |
| SCHEMBL22900019 | 0.79 | MCL1 (0.41) | ALDH1A1FAAHMEN1KMT2ARECQL | |
| SCHEMBL929623 | 0.79 | HPGD (0.32) | RECQLHPGD | |
| SCHEMBL20734766 | 0.78 | RECQL (0.32) | RECQL | |
| SCHEMBL12335913 | 0.78 | FAAH (0.40) | ALDH1A1MAPTTDP1LMNAPTGS2 | |
| SCHEMBL24756552 | 0.77 | TDP1 (0.52) | ALDH1A1MAPTTDP1LMNAPTGS2 | |
| SCHEMBL931025 | 0.76 | HDAC3 (0.38) | MEN1KMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL23017806 | 0.75 | TDP1 (0.41) | ALDH1A1MAPTTDP1LMNAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760685-B1 | THIOLATION OF PROTEINS FOR RADIONUCLIDE-BASED RADIOIMMUNODETECTION AND RADIOIMMUNOTHERAPY | IMMUNOMEDICS INC (US) | 2003-08-27 | — | — | EP | claimed |
| US-6010680-A | Thiolation of proteins for radionuclide-based radioimmunodetection and radioimmunotherapy | IMMUNOMEDICS, INC. (US) | 2000-01-04 | — | — | US | claimed |
| US-5772981-A | Thiolation of proteins for radionuclide-based radioimmunodetection and radioimmunotherapy | IMMUNOMEDICS, INC. (US) | 1998-06-30 | — | — | US | claimed |
| EP-0760685-B1 | THIOLATION OF PROTEINS FOR RADIONUCLIDE-BASED RADIOIMMUNODETECTION AND RADIOIMMUNOTHERAPY | IMMUNOMEDICS INC (US) | 2003-08-27 | — | — | EP | disclosed |