Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.67 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.60 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1527156 | 0.91 | TYR (0.72) | TYRTRIM24TRIM33ALDH1A1ALOX12 | |
| Carvacrol SCHEMBL6057359 | 0.86 | TYR (0.66) | TYRTRIM24TRIM33ALDH1A1ALOX12 | |
| P-Cymene SCHEMBL28761802 | 0.83 | TRIM24 (0.60) | TYRTRIM24TRIM33ALDH1A1ALOX12 | |
| Cuminaldehyde SCHEMBL6980858 | 0.81 | TYR (0.59) | TYRTRIM24TRIM33ALDH1A1CA1 | |
| Chamaecin SCHEMBL676459 | 0.80 | TYR (1.00) | TYRTRIM24TRIM33ALDH1A1ALOX12 | |
| SCHEMBL14354420 | 0.79 | TYR (0.55) | TYRTRIM24TRIM33KDM4EMAPT | |
| SCHEMBL12834530 | 0.78 | ERN1 (0.60) | TYRERN1 | |
| Salicyladehyde SCHEMBL27610933 | 0.78 | TRIM24 (0.90) | TYRTRIM24TRIM33ALDH1A1CA1 | |
| Salicyladehyde SCHEMBL10454896 | 0.78 | TRIM24 (0.90) | TYRTRIM24TRIM33ALDH1A1CA1 | |
| Salicyladehyde SCHEMBL15395 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334107-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | Basell Polyolefine GmbH (DE) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002032908-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2002-04-25 | — | — | WO | disclosed |