Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | DGKA | P23743 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CETP | P11597 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11124646 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL8781113 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL5280306 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL772826 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL22819559 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL11123903 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL7096716 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL15577118 | 0.95 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL15203715 | 0.95 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL16344688 | 0.95 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPK1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725772-B1 | PHYTOSPHINGOSINE-BASED CERAMIDE I ANALOGS | COSMOFERM BV (NL) | 2003-08-20 | — | — | EP | disclosed |
| US-6054599-A | DRUGS, COSMETICS; SKIN DISORDERS | DSM N.V. (NL) | 2000-04-25 | — | — | US | disclosed |
| US-5919960-A | Phytosphingosine-based ceramide I analogs | GIST-BROCADES, B.V. (NL) | 1999-07-06 | — | — | US | disclosed |
| EP-0725772-A1 | PHYTOSPHINGOSINE-BASED CERAMIDE I ANALOGS | GIST-BROCADES B.V. (NL) | 1996-08-14 | — | — | EP | disclosed |
| WO-1995011881-A1 | PHYTOSPHINGOSINE-BASED CERAMIDE I ANALOGS | GIST-BROCADES N.V. (NL) | 1995-05-04 | — | — | WO | disclosed |