SCHEMBL7095007

SCHEMBL7095007

O=C1NCCCCC1NCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VEGFA P15692 1/20 0.61
EGLN1 Q9GZT9 1/20 0.61
ALDH1A1 P00352 2/20 0.52
KDM4E B2RXH2 1/20 0.48
FPR2 P25090 1/20 0.45
BACE1 P56817 1/20 0.45
RAB9A P51151 2/20 0.44
HTT P42858 1/20 0.43
CCR2 P41597 4/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
ADORA2A P29274 1/20 0.42
ADORA1 P30542 1/20 0.42
MAPK1 P28482 1/20 0.42
PSEN1 P49768 1/20 0.42
PSEN2 P49810 1/20 0.42
APH1B Q8WW43 1/20 0.42
NCSTN Q92542 1/20 0.42
APH1A Q96BI3 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15398330 0.89 VEGFA (0.49) VEGFAEGLN1ALDH1A1BACE1RAB9A
SCHEMBL3744061 0.89 VEGFA (0.49) VEGFAEGLN1ALDH1A1BACE1RAB9A
SCHEMBL1347170 0.88 HTR2C (0.51) VEGFAEGLN1KDM4E
SCHEMBL4002909 0.85 VEGFA (0.47) VEGFAEGLN1ALDH1A1KDM4EFPR2
SCHEMBL4007580 0.85 VEGFA (0.47) VEGFAEGLN1ALDH1A1KDM4EFPR2
SCHEMBL5567270 0.85 VEGFA (0.47) VEGFAEGLN1ALDH1A1KDM4ERAB9A
SCHEMBL1347137 0.84 VEGFA (0.46) VEGFAEGLN1ALDH1A1BACE1RAB9A
SCHEMBL1346755 0.83 HTR2C (0.55) VEGFAEGLN1KDM4E
SCHEMBL5567663 0.81 ALDH1A1 (0.50) VEGFAEGLN1ALDH1A1KDM4EBACE1
SCHEMBL4013822 0.81 VEGFA (0.43) VEGFAEGLN1ALDH1A1FPR2BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118994009-A Preparation method of mono-benzyl amino caprolactam, application thereof and functional nylon-6 中国石油化工股份有限公司 2024-11-22 CN claimed
EP-0294062-B1 RESIN COMPOSITIONS AND MOLDED PRODUCTS THEREOF UBE INDUSTRIES, LTD. (JP) 1993-09-01 EP claimed
US-4879341-A WATERPROOF, FLEXIBILE, RIDIGITY, UBE INDUSTRIES, LTD. (JP) 1989-11-07 US claimed
JP-59055860-A None JP disclosed
CN-118994009-A Preparation method of mono-benzyl amino caprolactam, application thereof and functional nylon-6 中国石油化工股份有限公司 2024-11-22 CN disclosed
CN-103694174-A Alpha- (N-benzyl) amino-caprolactam compound and preparation method and application thereof NANJING UNIVERSITY OF TECHNOLOGY 2014-04-02 CN disclosed
CN-103694174-A Alpha- (N-benzyl) amino-caprolactam compound and preparation method and application thereof NANJING UNIVERSITY OF TECHNOLOGY 2014-04-02 CN disclosed
EP-0815084-B1 LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE PROCTER & GAMBLE (US) 2003-08-27 EP disclosed
EP-0294062-B1 RESIN COMPOSITIONS AND MOLDED PRODUCTS THEREOF UBE INDUSTRIES, LTD. (JP) 1993-09-01 EP disclosed
EP-0128775-B1 RESINOUS COMPOSITION TORAY INDUSTRIES, INC. (JP) 1989-11-15 EP disclosed
US-4879341-A WATERPROOF, FLEXIBILE, RIDIGITY, UBE INDUSTRIES, LTD. (JP) 1989-11-07 US disclosed
EP-0294062-A2 Resin compositions and molded products thereof UBE INDUSTRIES, LTD. (JP) 1988-12-07 EP disclosed
US-4612346-A BLEND OF POLYAMIDE AND MODIFIED POLYOLEFIN TORAY INDUSTRIES, INC. (JP) 1986-09-16 US disclosed
EP-0128775-A2 Resinous composition TORAY INDUSTRIES, INC. (JP) 1984-12-19 EP disclosed
JP-S5955860-A PREPARATION OF OPTICAL ACTIVE PHENYLGLYCINE TORAY IND INC 1984-03-31 JP disclosed