SCHEMBL7095071

SCHEMBL7095071

CC1COC(=O)C2(CC2C)C2(CC2C)C(=O)O1

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.31
CA1 P00915 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8596087 0.80 SMN1; SMN2 (0.33) SMN1; SMN2CA1CA9
SCHEMBL7194381 0.73 SMN1; SMN2 (0.40) SMN1; SMN2CA1CA9
SCHEMBL6402462 0.67 CA1 (0.39) SMN1; SMN2CA1CA9
Propylene Carbonate SCHEMBL15309 0.66
Propylene Carbonate SCHEMBL3381047 0.66
Propylene Carbonate SCHEMBL748245 0.66
Propylene Carbonate SCHEMBL1695395 0.66 SMN1; SMN2 (0.43) SMN1; SMN2CA1CA9
Propylene Carbonate SCHEMBL30481548 0.66
SCHEMBL12616582 0.66 SMN1; SMN2 (0.39) SMN1; SMN2MAPTCA1CA9
Propylene Carbonate SCHEMBL4639782 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1334172-A1 MACHINING FLUID AND METHOD OF MACHINING Milacron Inc. (US) 2003-08-13 EP disclosed
WO-2002061022-A1 MACHINING FLUID AND METHOD OF MACHINING MILACRON INC. (US) 2002-08-08 WO disclosed
US-6316394-B1 SULFURIZED ORGANIC LUBRICANTS AND HALOGENATED ORGANIC LUBRICANTS MILACRON INC. 2001-11-13 US disclosed
US-5704961-A MONOCARBOXYLIC ACIDS, POLYCARBOXYLIC ACIDS OR THEIR SALTS HUDSON ALICE P (US) 1998-01-06 US disclosed
US-4668722-A Hindered piperidinoalcohol 1,1,1-trioxyalkane stabilizers MACK GERRY P 1987-05-26 US disclosed
US-4448586-A ALKYL OR ALKENYL SUCCINIC ACID AND ANESTER THEREOF, A GLYCOL, AND A DIMER OR TRIMER ACID ETHYL CORPORATION (US) 1984-05-15 US disclosed