Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR4 | P46093 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4689282 | 0.99 | USP2 (0.41) | GPR4USP2SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL26635835 | 0.85 | USP2 (0.41) | USP2SMN1; SMN2L3MBTL1TSHRLMNA | |
| SCHEMBL2958409 | 0.85 | USP2 (0.36) | GPR4USP2SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL240646 | 0.85 | SMN1; SMN2 (0.43) | GPR4USP2SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL26636170 | 0.84 | USP2 (0.40) | USP2SMN1; SMN2L3MBTL1TSHRLMNA | |
| SCHEMBL7095095 | 0.83 | USP2 (0.39) | USP2SMN1; SMN2L3MBTL1TSHRLMNA | |
| SCHEMBL3314428 | 0.83 | SMN1; SMN2 (0.41) | GPR4USP2SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL16130103 | 0.82 | USP2 (0.45) | GPR4USP2SMN1; SMN2TSHRDDB1 | |
| SCHEMBL26665513 | 0.82 | USP2 (0.47) | GPR4USP2SMN1; SMN2TSHRDDB1 | |
| SCHEMBL27086843 | 0.81 | L3MBTL1 (0.39) | USP2SMN1; SMN2L3MBTL1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286967-A1 | CYCLOHEXANE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LTD. (GB) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001087838-A1 | CYCLOHEXANE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LIMITED (GB) | 2001-11-22 | — | — | WO | disclosed |