Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18414188 | 0.90 | EPHX2 (0.46) | EPHX2HPGDCYP2D6CYP2C19NR1H2 | |
| SCHEMBL14096740 | 0.90 | RECQL (0.46) | EPHX2HPGDCYP2D6CYP2C19NR1H2 | |
| SCHEMBL8558174 | 0.81 | RECQL (0.50) | EPHX2CYP2D6L3MBTL1RECQL | |
| SCHEMBL7099855 | 0.81 | TSHR (0.54) | EPHX2HPGDCYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL16724722 | 0.78 | MEN1 (0.47) | HPGDNR1H2CAPN1 | |
| SCHEMBL26242694 | 0.78 | MAPT (0.47) | EPHX2HPGDCYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL13765209 | 0.77 | CYP2D6 (0.37) | EPHX2HPGDCYP2D6CYP2C19NR1H2 | |
| SCHEMBL17232599 | 0.77 | APLNR (0.42) | EPHX2CYP2D6L3MBTL1LMNARECQL | |
| SCHEMBL17660249 | 0.76 | HPGD (0.45) | EPHX2HPGDCYP2D6CYP2C19NR1H2 | |
| SCHEMBL9098228 | 0.76 | CA7 (0.41) | EPHX2CYP2D6CYP2C19CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |
| EP-0815084-A1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | THE PROCTER & GAMBLE COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |
| US-5672598-A | MATRIX METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| WO-1996029313-A1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | THE PROCTER & GAMBLE COMPANY (US) | 1996-09-26 | — | — | WO | disclosed |