Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | BLK | P51451 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 3/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5235675 | 0.94 | PTGDR2 (0.51) | PTGDR2SCDMGLLPSEN1PSEN2 | |
| SCHEMBL8822060 | 0.84 | POLB (0.48) | PTGDR2BLKBTKSCDMGLL | |
| SCHEMBL7095938 | 0.82 | PTGDR2 (0.47) | PTGDR2BLKBTKSCDMGLL | |
| SCHEMBL8822065 | 0.81 | PTGDR2 (0.46) | PTGDR2BLKBTKSCDMGLL | |
| SCHEMBL4018735 | 0.81 | PTGDR2 (0.45) | PTGDR2SCDMGLLTP53MAPT | |
| SCHEMBL7853448 | 0.81 | CALML3 (0.43) | PTGDR2SCD | |
| SCHEMBL7853449 | 0.81 | CALML3 (0.43) | PTGDR2SCD | |
| SCHEMBL13054805 | 0.79 | SCD (0.44) | PTGDR2SCDMGLLTP53MAPT | |
| SCHEMBL7839750 | 0.78 | MGLL (0.54) | PTGDR2SCDMGLLTP53MAPT | |
| SCHEMBL7841588 | 0.78 | POLB (0.54) | PTGDR2SCDMGLLTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286998-A1 | OXAZOLIDINONE DERIVATIVES WITH ANTIBIOTIC ACTIVITY | AstraZeneca AB (SE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001081350-A1 | OXAZOLIDINONE DERIVATIVES WITH ANTIBIOTIC ACTIVITY | ASTRAZENECA AB (SE) | 2001-11-01 | — | — | WO | disclosed |