Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.63 |
| ▸ | ITGAV | P06756 | 18/20 | 0.63 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5494840 | 0.91 | ITGB3 (0.74) | ITGB3ITGAVITGA2B | |
| SCHEMBL7091035 | 0.77 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7095827 | 0.77 | SRD5A2 (0.41) | ITGB3ITGAVITGA2B | |
| SCHEMBL344876 | 0.77 | ITGB3 (0.67) | ITGB3ITGAVITGA2B | |
| SCHEMBL7916989 | 0.76 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL8739838 | 0.76 | ITGB3 (0.79) | ITGB3ITGAVITGA2B | |
| SCHEMBL6951971 | 0.76 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL245523 | 0.75 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL31321063 | 0.75 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL6946521 | 0.75 | ITGB3 (1.00) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910563-B1 | INTEGRIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6008213-A | A INHIBITOR OF VITRONECTIN RECEPTOR AND FIBRINOGEN RECEPTOR; USEFUL FOR INHIBITING PLATELET AGGREGATION AND OSTEOPOROSIS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-12-28 | — | — | US | disclosed |
| EP-0910563-A4 | — | — | 1999-04-28 | — | — | EP | disclosed |
| EP-0910563-A1 | INTEGRIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-04-28 | — | — | EP | disclosed |
| WO-1997001540-A1 | INTEGRIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-01-16 | — | — | WO | disclosed |