Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090358 | 0.81 | CA2 (0.68) | CA2CA1GRIK1GRIK2SLC1A2 | |
| SCHEMBL2481659 | 0.81 | CA2 (0.68) | CA2CA1GRIK1GRIK2SLC1A2 | |
| SCHEMBL4658540 | 0.81 | CA2 (0.68) | CA2CA1GRIK1GRIK2SLC1A2 | |
| SCHEMBL3235440 | 0.81 | CA2 (0.68) | CA2CA1GRIK1GRIK2SLC1A2 | |
| SCHEMBL80651 | 0.81 | CA2 (0.68) | CA2CA1GRIK1GRIK2SLC1A2 | |
| SCHEMBL10866230 | 0.81 | CA2 (0.68) | CA2CA1GRIK1GRIK2SLC1A2 | |
| SCHEMBL2089080 | 0.81 | CA2 (0.68) | CA2CA1GRIK1GRIK2SLC1A2 | |
| SCHEMBL16098865 | 0.81 | CA2 (0.68) | CA2CA1GRIK1GRIK2SLC1A2 | |
| SCHEMBL20746502 | 0.81 | CA2 (0.68) | CA2CA1GRIK1GRIK2SLC1A2 | |
| SCHEMBL10866159 | 0.81 | CA2 (0.68) | CA2CA1GRIK1GRIK2SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |