SCHEMBL7095605

SCHEMBL7095605

O=C(Nc1ccccc1)Oc1cc2ccccc2cc1O

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.54
ALDH1A1 P00352 4/20 0.51
GAA P10253 3/20 0.51
HTT P42858 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
KMT2A Q03164 2/20 0.51
KDM4E B2RXH2 2/20 0.50
BLM P54132 1/20 0.50
MAPT P10636 3/20 0.49
BCHE P06276 1/20 0.48
ACHE P22303 1/20 0.48
FAAH O00519 1/20 0.48
RAB9A P51151 2/20 0.48
CYP1A2 P05177 1/20 0.47
RAD51 Q06609 1/20 0.46
NPC1 O15118 1/20 0.46
PTGS1 P23219 1/20 0.46
PTGS2 P35354 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9750007 0.97 HSP90AA1 (0.51) HSP90AA1ALDH1A1GAAHTTSMN1; SMN2
SCHEMBL9411667 0.88 ATM (0.59) HSP90AA1ALDH1A1KMT2AKDM4EMAPT
SCHEMBL10437732 0.87 NPC1 (0.63) ALDH1A1GAAHTTSMN1; SMN2KMT2A
SCHEMBL9622025 0.86 SMN1; SMN2 (0.59) ALDH1A1GAAHTTSMN1; SMN2KMT2A
SCHEMBL10437702 0.81 MEN1 (0.65) ALDH1A1HTTSMN1; SMN2KMT2ABLM
SCHEMBL9332843 0.80 MAPT (0.53) ALDH1A1GAASMN1; SMN2KMT2AKDM4E
SCHEMBL8782304 0.80 ALDH1A1 (0.58) ALDH1A1GAAKMT2AKDM4EMAPT
SCHEMBL2760999 0.79 HPGD (0.46) ALDH1A1GAASMN1; SMN2KMT2AKDM4E
SCHEMBL9621986 0.79 TRPV1 (0.58) ALDH1A1GAAKMT2AKDM4EMAPT
SCHEMBL9622065 0.79 KMT2A (0.53) ALDH1A1GAAHTTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1268674-A2 BLACK TRIS AZO METAL COMPLEX DYES Clariant GmbH (DE) 2003-01-02 EP disclosed
WO-2001072906-A2 BLACK TRIS AZO METAL COMPLEX DYES CLARIANT GMBH (DE) 2001-10-04 WO disclosed
EP-0391264-B1 Reactive dyes with two or three halogen-N-heterocycles as reactive groups BASF AG (DE) 1995-01-18 EP disclosed
EP-0352682-B1 Twice reactive dyes and benzyl compounds as their intermediary products BASF AG (DE) 1994-02-02 EP disclosed
EP-0199973-B1 PROCESS FOR THE PRODUCTION ON THE FIBRE OF WATER INSOLUBLE AZO DYES HOECHST AKTIENGESELLSCHAFT (DE) 1992-04-15 EP disclosed
EP-0391264-A1 Reactive dyes with two or three halogen-N-heterocycles as reactive groups BASF Aktiengesellschaft (DE) 1990-10-10 EP disclosed
EP-0300390-B1 TRIFLUOROMETHYL-ALKOXY-ANILIN, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE ICE-COLOUR TECHNIQUE HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-29 EP disclosed
EP-0362725-A1 Process for producing water insoluble azo dyes on the fibre according to the ice-colour technique HOECHST AKTIENGESELLSCHAFT (DE) 1990-04-11 EP disclosed
EP-0362729-A1 Process for producing water insoluble azo dyes on the fibre HOECHST AKTIENGESELLSCHAFT (DE) 1990-04-11 EP disclosed
EP-0218206-B1 DISAZO PIGMENTS HAVING A PIPERAZINE BRIDGING MEMBER BASF Aktiengesellschaft (DE) 1990-02-07 EP disclosed
EP-0218206-A2 Disazo pigments having a piperazine bridging member BASF Aktiengesellschaft (DE) 1987-04-15 EP disclosed
EP-0119441-B1 REACTIVE DYES WITH SUBSTITUTED 4-FLUOROPYRIDAZ-6-ONE GROUPS BASF Aktiengesellschaft (DE) 1987-02-25 EP disclosed
EP-0199973-A2 Process for the production on the fibre of water insoluble azo dyes HOECHST AKTIENGESELLSCHAFT (DE) 1986-11-05 EP disclosed
EP-0196023-A2 4,4'-Disazo compounds of 3,3'-dialkoxybiphenylene, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1986-10-01 EP disclosed
EP-0119441-A2 Reactive dyes with substituted 4-fluoropyridaz-6-one groups BASF Aktiengesellschaft (DE) 1984-09-26 EP disclosed
EP-0031099-B1 COMPOUNDS WITH REACTIVE RESTS AND THEIR USE IN DYEING FIBRES BASF Aktiengesellschaft (DE) 1984-07-18 EP disclosed
EP-0016388-B1 PROCESS FOR THE PREPARATION OF DIAZONIUM SALT SOLUTIONS HOECHST AKTIENGESELLSCHAFT (DE) 1983-01-12 EP disclosed
EP-0037465-A2 Amino azo compounds BASF Aktiengesellschaft (DE) 1981-10-14 EP disclosed
EP-0031099-A2 Compounds with reactive rests and their use in dyeing fibres BASF Aktiengesellschaft (DE) 1981-07-01 EP disclosed
EP-0016388-A1 Process for the preparation of diazonium salt solutions HOECHST AKTIENGESELLSCHAFT (DE) 1980-10-01 EP disclosed