⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741012 | 1.00 | — | — | |
| SCHEMBL20104825 | 1.00 | — | — | |
| SCHEMBL43248 | 1.00 | — | — | |
| SCHEMBL1485907 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL7002319 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL18662816 | 0.98 | — | — | |
| SCHEMBL42115 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL7307173 | 0.95 | — | — | |
| SCHEMBL1492690 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL1492697 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3113780-B1 | HIV PROTEASE INHIBITORS | MERCK SHARP & DOHME (US) | 2019-08-14 | — | — | EP | disclosed |
| US-20030109549-A1 | 2-Substituted-1-piperidyl benzimidazole compounds as ORL1-receptor agonists | ITO FUMITAKA (JP) | 2003-06-12 | — | — | US | disclosed |
| EP-1102762-B1 | 2-SUBSTITUTED-1-PIPERIDYL BENZIMIDAZOLE COMPOUNDS AS ORL1-RECEPTOR AGONISTS | PFIZER (US) | 2002-11-13 | — | — | EP | disclosed |
| EP-1102762-A2 | 2-SUBSTITUTED-1-PIPERIDYL BENZIMIDAZOLE COMPOUNDS AS ORL1-RECEPTOR AGONISTS | PFIZER INC. (US) | 2001-05-30 | — | — | EP | disclosed |
| US-6172067-B1 | ANALGESICS, ANTIINFLAMMATORY AGENTS | PFIZER INC. | 2001-01-09 | — | — | US | disclosed |
| WO-2000008013-A2 | 2-SUBSTITUTED-1-PIPERIDYL BENZIMIDAZOLE COMPOUNDS AS ORL1-RECEPTOR AGONISTS | PFIZER PHARMACEUTICALS INC. (JP) | 2000-02-17 | — | — | WO | disclosed |