Riboprine

SCHEMBL7096367

CC(C)=CCNc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O.CCC1(c2ccncc2)CCC(=O)NC1=O

nearest known ligand 0.53

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	TP53	P04637	2/20	0.53

▸	LMNA	P02545	1/20	0.53

▸	ALOX15	P16050	1/20	0.53

▸	TSHR	P16473	1/20	0.53

▸	HTT	P42858	1/20	0.53

▸	RXFP1	Q9HBX9	1/20	0.53

▸	SLC29A1	Q99808	4/20	0.50

▸	ADORA3	P0DMS8	4/20	0.48

▸	ADORA1	P30542	2/20	0.48

▸	ADORA2A	P29274	1/20	0.48

▸	TDP1	Q9NUW8	1/20	0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Riboprine SCHEMBL28121660	0.89	SLC29A1 (0.46)	TP53LMNAALOX15TSHRHTT
Riboprine SCHEMBL28250734	0.82	SLC29A1 (0.39)	TP53LMNAALOX15TSHRHTT
Riboprine SCHEMBL28124720	0.81	SLC29A1 (0.39)	TP53LMNAALOX15TSHRHTT
Riboprine SCHEMBL4600	0.80	TP53 (0.79)	TP53LMNAALOX15TSHRHTT
Riboprine SCHEMBL1763190	0.80	TP53 (0.79)	TP53LMNAALOX15TSHRHTT
Riboprine SCHEMBL29552839	0.80	TP53 (0.79)	TP53LMNAALOX15TSHRHTT
Riboprine SCHEMBL18870819	0.80	TP53 (0.79)	TP53LMNAALOX15TSHRHTT
Riboprine SCHEMBL4599	0.80	TP53 (0.79)	TP53LMNAALOX15TSHRHTT
Riboprine SCHEMBL4815729	0.80	TP53 (0.79)	TP53LMNAALOX15TSHRHTT
Riboprine SCHEMBL18503566	0.80	TP53 (0.79)	TP53LMNAALOX15TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2003097835-A2	PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CANCER	MOLECULAR ENGINES LABORATORIES (FR)	2003-11-27	—	—	WO	disclosed