SCHEMBL7096749

SCHEMBL7096749

Clc1cc(Cl)cc(C(Cl)(Cl)Cl)c1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.53
CYP3A4 P08684 3/20 0.40
TP53 P04637 1/20 0.40
MAPK1 P28482 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 2/20 0.35
AHR P35869 2/20 0.33
TPMT P51580 1/20 0.33
HIF1A Q16665 1/20 0.32
RECQL P46063 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
IDO1 P14902 1/20 0.31
HTR3E A5X5Y0 1/20 0.31
HTR3B O95264 1/20 0.31
HTR3A P46098 1/20 0.31
HTR3D Q70Z44 1/20 0.31
HTR3C Q8WXA8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7930028 0.93 TSHR (0.44) TSHRCYP3A4TP53MAPK1TDP1
SCHEMBL7928488 0.85 TSHR (0.50) TSHRCYP3A4MAPK1TDP1ALDH1A1
SCHEMBL4478239 0.80 TSHR (0.53) TSHRCYP3A4TP53MAPK1TDP1
SCHEMBL1538847 0.78 TSHR (0.47) TSHRCYP3A4MAPK1TDP1
SCHEMBL10974819 0.77 TSHR (0.33) TSHRTP53MAPK1TDP1HIF1A
SCHEMBL10974821 0.77 TSHR (0.38) TSHRIDO1
SCHEMBL7928485 0.77 TSHR (0.44) TSHRCYP3A4MAPK1TDP1
SCHEMBL9403849 0.75 TSHR (0.47) TSHRCYP3A4TP53ALDH1A1AHR
1,3,5-Trichlorobenzene SCHEMBL429512 0.73
1,3,5-Trichlorobenzene SCHEMBL23244766 0.72 TSHR (0.61) TSHRCYP3A4TP53MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743438-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2026-05-20 EP claimed
EP-4665705-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2025-12-24 EP claimed
WO-2025068995-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2025-04-03 WO claimed
WO-2024171098-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2024-08-22 WO claimed
EP-4743438-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2026-05-20 EP disclosed
EP-4665705-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2025-12-24 EP disclosed
WO-2025068995-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2025-04-03 WO disclosed
WO-2024171098-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2024-08-22 WO disclosed
CN-108069853-B Synthetic method of 3, 5-dichlorobenzoyl chloride 江西吉翔医药化工有限公司 2020-12-22 CN disclosed
EP-0921115-B1 Process for making aromatic nitriles AMERICAN WRECKING CORP OF NEW (US) 2003-09-03 EP disclosed
EP-0921115-A2 Process for making aromatic nitriles OCCIDENTAL CHEMICAL CORPORATION, Occidental Tower (US) 1999-06-09 EP disclosed
US-5866709-A Process for making aromatic nitriles OCCIDENTAL CHEMICAL CORP (US) 1999-02-02 US disclosed
US-4163753-A FROM AN ALIPHATIC ACID ANHYDRIDE AND A TRICHLOROMETHYL AROMATIC COMPOUND Diaz Chemical Corporation (US) 1979-08-07 US disclosed