Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3910392 | 0.81 | MGAM (0.46) | LMNATSHRMAPTALDH1A1HTT | |
| SCHEMBL181918 | 0.81 | LMNA (0.43) | LMNATSHRMAPTCYP2D6ALDH1A1 | |
| SCHEMBL7099334 | 0.81 | LMNA (0.41) | LMNATSHRMAPTCYP2D6ALDH1A1 | |
| SCHEMBL229792 | 0.80 | TSHR (0.50) | LMNATSHRMAPTCYP2D6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29090137 | 0.79 | LMNA (0.42) | LMNATSHRMAPTCYP2D6ALDH1A1 | |
| SCHEMBL7101885 | 0.78 | LMNA (0.43) | LMNATSHRMAPTALDH1A1ALOX15 | |
| SCHEMBL28727541 | 0.78 | LMNA (0.48) | LMNATSHRMAPTCYP2D6ALDH1A1 | |
| SCHEMBL18152012 | 0.78 | LMNA (0.48) | LMNATSHRMAPTCYP2D6ALDH1A1 | |
| SCHEMBL28875912 | 0.78 | LMNA (0.48) | LMNATSHRMAPTCYP2D6ALDH1A1 | |
| SCHEMBL28315849 | 0.78 | LMNA (0.48) | LMNATSHRMAPTCYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038861-B1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6593488-B1 | Reacting 2-fluorocarboxylate with carboxylate | UBE INDUSTRIES, LTD. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1038861-A1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES LIMITED (JP) | 2000-09-27 | — | — | EP | disclosed |