Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 10/20 | 0.58 |
| ▸ | DRD2 | P14416 | 9/20 | 0.58 |
| ▸ | HRH1 | P35367 | 4/20 | 0.58 |
| ▸ | HRH2 | P25021 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | HTR2B | P41595 | 2/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | HTR5A | P47898 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098164 | 1.00 | DRD3 (0.58) | DRD3DRD2HRH1HRH2HTR2A | |
| SCHEMBL7100743 | 1.00 | DRD3 (0.58) | DRD3DRD2HRH1HRH2HTR2A | |
| Hydrochloric Acid SCHEMBL7103056 | 0.99 | DRD3 (0.57) | DRD3DRD2HRH1HRH2HTR2A | |
| SCHEMBL7099317 | 0.96 | DRD3 (0.51) | DRD3DRD2HRH1HRH2HTR2A | |
| SCHEMBL7098299 | 0.96 | DRD3 (0.51) | DRD3DRD2HRH1HRH2HTR2A | |
| SCHEMBL7102250 | 0.95 | DRD3 (0.57) | DRD3DRD2HRH1HRH2HTR2A | |
| SCHEMBL7098325 | 0.95 | DRD3 (0.57) | DRD3DRD2HRH1HRH2HTR2A | |
| SCHEMBL7097378 | 0.94 | DRD3 (0.57) | DRD3DRD2HRH1HRH2HTR2A | |
| SCHEMBL7102358 | 0.94 | DRD3 (0.57) | DRD3DRD2HRH1HRH2HTR2A | |
| SCHEMBL7101905 | 0.85 | ACHE (0.50) | DRD3DRD2HRH1HTR2ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1020443-A1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |