Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 20/20 | 0.73 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095983 | 0.86 | SRC (0.58) | SRCEGFRFYNMAP2K1 | |
| SCHEMBL7148997 | 0.86 | SRC (0.73) | SRCEGFRFYNMAP2K1 | |
| SCHEMBL3227726 | 0.84 | SRC (1.00) | SRCEGFRFYNMAP2K1 | |
| SCHEMBL7104720 | 0.84 | SRC (0.72) | SRCEGFRFYNMAP2K1 | |
| SCHEMBL7148769 | 0.78 | SRC (0.59) | SRCEGFRFYNMAP2K1 | |
| SCHEMBL7182522 | 0.74 | SRC (0.57) | SRCEGFRFYNMAP2K1 | |
| SCHEMBL7249493 | 0.74 | SRC (0.59) | SRCEGFRFYNMAP2K1 | |
| SCHEMBL3216567 | 0.73 | SRC (1.00) | SRCEGFRFYNMAP2K1 | |
| SCHEMBL3225591 | 0.72 | SRC (0.85) | SRCEGFRFYNMAP2K1 | |
| SCHEMBL7095265 | 0.72 | SRC (0.54) | SRCEGFRFYNMAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268431-A1 | 3-CYANOQUINOLINES,3-CYANO-1,6-NAPHTHYRIDINES, AND 3-CYANO-1,7-NAPHTHYRIDINES AS PROTEIN KINASE INHIBITORS | Wyeth (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001072711-A1 | 3-CYANOQUINOLINES,3-CYANO-1,6-NAPHTHYRIDINES, AND 3-CYANO-1,7-NAPHTHYRIDINES AS PROTEIN KINASE INHIBITORS | WYETH (US) | 2001-10-04 | — | — | WO | disclosed |