Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 18/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3215738 | 0.86 | SRC (0.80) | SRCEGFRFYNMAP2K1ABL1 | |
| SCHEMBL7247799 | 0.83 | RET (0.47) | SRCEGFRMAP2K1RET | |
| SCHEMBL7247623 | 0.83 | SRC (0.56) | SRCFYN | |
| SCHEMBL3230492 | 0.79 | SRC (0.82) | SRCEGFRFYNMAP2K1ABL1 | |
| SCHEMBL7249188 | 0.78 | MAP2K1 (0.46) | SRCMAP2K1RET | |
| SCHEMBL7148769 | 0.78 | SRC (0.59) | SRCEGFRFYNMAP2K1ABL1 | |
| SCHEMBL7104720 | 0.75 | SRC (0.72) | SRCEGFRFYNMAP2K1 | |
| SCHEMBL3222377 | 0.75 | SRC (0.70) | SRCEGFRFYNMAP2K1 | |
| SCHEMBL3224349 | 0.74 | SRC (1.00) | SRCEGFRFYNMAP2K1 | |
| SCHEMBL7148997 | 0.74 | SRC (0.73) | SRCEGFRFYNMAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521618-B2 | Antineoplastic agents, agents for treatment of osteoporosis and polycystic kidney disease | WYETH | 2003-02-18 | — | — | US | disclosed |