SCHEMBL709808

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27462412	0.89	SMN1; SMN2 (0.66)	ALDH1A1TDP1TSHRL3MBTL1MAPK1
	SCHEMBL5836722	0.86	HTT (0.57)	ALDH1A1TDP1TSHRL3MBTL1MAPK1
	SCHEMBL10930452	0.85	ALDH1A1 (0.58)	ALDH1A1TDP1TSHRL3MBTL1MAPK1
	SCHEMBL707627	0.83	CTNNB1 (0.51)	ALDH1A1TDP1TSHRL3MBTL1SMN1; SMN2
	SCHEMBL639	0.82	KMT2A (0.55)	ALDH1A1L3MBTL1MAPK1SMN1; SMN2KMT2A
	SCHEMBL9178840	0.81	ALDH1A1 (0.56)	ALDH1A1TDP1TSHRL3MBTL1MAPK1
	SCHEMBL9574717	0.78	HTT (0.73)	ALDH1A1TDP1TSHRL3MBTL1MAPK1
	SCHEMBL2112521	0.77	HTT (0.63)	ALDH1A1TDP1TSHRL3MBTL1MAPK1
	SCHEMBL6167480	0.77	NR4A2 (0.59)	ALDH1A1TDP1TSHRL3MBTL1MAPK1
	SCHEMBL4415350	0.76	HTT (0.75)	ALDH1A1TDP1TSHRL3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.