Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102700 | 0.93 | ITGA4 (0.47) | NPSR1MEN1KMT2AFFAR1L3MBTL1 | |
| SCHEMBL7102696 | 0.93 | ITGA4 (0.47) | NPSR1MEN1KMT2AFFAR1L3MBTL1 | |
| SCHEMBL7103891 | 0.87 | ITGB1 (0.56) | ITGA4ITGB1 | |
| SCHEMBL7103896 | 0.87 | ITGB1 (0.56) | ITGA4ITGB1 | |
| SCHEMBL7099196 | 0.85 | ITGA4 (0.57) | NPSR1MEN1KMT2AITGA4SMN1; SMN2 | |
| SCHEMBL7099197 | 0.85 | ITGA4 (0.57) | NPSR1MEN1KMT2AITGA4SMN1; SMN2 | |
| SCHEMBL7105450 | 0.84 | ITGB1 (0.54) | ITGA4ITGB1 | |
| SCHEMBL7102026 | 0.84 | ITGB1 (0.54) | ITGA4ITGB1 | |
| SCHEMBL7098697 | 0.84 | NPSR1 (0.52) | NPSR1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL7098693 | 0.84 | NPSR1 (0.52) | NPSR1MEN1KMT2ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991619-B1 | INHIBITORS OF ALPHA 4-BETA 1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2003-09-10 | — | — | EP | claimed |