Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | TRHDE | Q9UKU6 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6499762 | 0.87 | KDM2B (0.41) | ALDH1A1PTGS2MEN1KMT2AKDM4C | |
| SCHEMBL7103533 | 0.86 | CYP1A2 (0.41) | ALDH1A1CPB2CPB1KDM4CTRHDE | |
| SCHEMBL6527840 | 0.85 | CDK5 (0.47) | CYP3A4CYP2C9CYP2C19CPB2CPB1 | |
| SCHEMBL6069460 | 0.85 | CDK5 (0.47) | CYP3A4CYP2C9CYP2C19CPB2CPB1 | |
| Hydrochloric Acid SCHEMBL7356305 | 0.84 | CDK5 (0.46) | CYP3A4CYP2C9CYP2C19CPB2CPB1 | |
| Hydrochloric Acid SCHEMBL6527838 | 0.84 | CDK5 (0.46) | CYP3A4CYP2C9CYP2C19CPB2CPB1 | |
| Hydrochloric Acid SCHEMBL5997862 | 0.84 | CDK5 (0.46) | CYP3A4CYP2C9CYP2C19CPB2CPB1 | |
| Hydrochloric Acid SCHEMBL6527843 | 0.84 | CDK5 (0.46) | CYP3A4CYP2C9CYP2C19CPB2CPB1 | |
| Hydrochloric Acid SCHEMBL6529050 | 0.83 | FNTA (0.40) | ALDH1A1CYP3A4CYP2C9CYP2C19CPB2 | |
| Hydrochloric Acid SCHEMBL6531456 | 0.83 | SMN1; SMN2 (0.41) | ALDH1A1KDM4EHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991619-B1 | INHIBITORS OF ALPHA 4-BETA 1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-20030130349-A1 | Inhibitors of alpha 4beta1 mediated cell adhesion | TANABE SEIYAKU CO., LTD. | 2003-07-10 | — | — | US | disclosed |
| EP-0991619-A1 | INHIBITORS OF $g(a) 4?$g(b) 1?MEDIATED CELL ADHESION | TANABE SEIYAKU CO., LTD. (JP) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998058902-A1 | INHIBITORS OF α4β1MEDIATED CELL ADHESION | TANABE SEIYAKU CO., LTD. (JP) | 1998-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130349-A1 | Inhibitors of alpha 4beta1 mediated cell adhesion | VCAM1, ICAM1, ITGB1 | ALDH1A1 100/4885KDM4E 2802/4885CYP3A4 1685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.