Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.39 |
| ▸ | CDC25B | P30305 | 3/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL711226 | 0.93 | SMO (0.41) | SMOPPARGPTPN1PTPN2CDC25B | |
| SCHEMBL10206637 | 0.93 | CYP3A4 (0.43) | SMOPTPN1PTPN2CDC25BPDE5A | |
| Trifluoroacetic Acid SCHEMBL709554 | 0.93 | CYP3A4 (0.43) | PPARGPDE5APDE4APDE4BPDE4C | |
| Trifluoroacetic Acid SCHEMBL712956 | 0.89 | GPR132 (0.45) | PPARGPTPN1LRRK2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL712435 | 0.89 | SMO (0.40) | SMOPPARGPTPN1PTPN2CDC25B | |
| Trifluoroacetic Acid SCHEMBL713332 | 0.88 | KMT2A (0.41) | SMOPTPN1PDE5APDE4APDE4B | |
| Trifluoroacetic Acid SCHEMBL711595 | 0.88 | LRRK2 (0.43) | PPARGPDE5APDE4APDE4BPDE4C | |
| Trifluoroacetic Acid SCHEMBL711105 | 0.86 | CYP1A1 (0.41) | SMOPTPN1PTPN2CDC25BCYP1A1 | |
| SCHEMBL2668132 | 0.86 | CYP3A4 (0.43) | SMOPTPN1PTPN2CDC25BPDE5A | |
| Trifluoroacetic Acid SCHEMBL711971 | 0.86 | CYP3A4 (0.43) | PDE5APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940837-B1 | IMIDAZOPYRIDINE COMPOUNDS | TAKEDA PHARMACEUTICAL (JP) | 2012-11-07 | — | — | EP | disclosed |
| US-8124617-B2 | Imidazopyridine compounds | TAKEDA SAN DIEGO, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20100069431-A1 | IMIDAZOPYRIDINE COMPOUNDS | TAKEDA SAN DIEGO, INC. | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069431-A1 | IMIDAZOPYRIDINE COMPOUNDS | GCK, GCKR, KHK | SMO 4431/4885PPARG 991/4885PTPN1 3316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.