Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | PAM | P19021 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6416791 | 0.92 | DGKA (0.47) | CYP1A2ALDH1A1DGKATSHRHTR6 | |
| SCHEMBL12551149 | 0.84 | CYP1A2 (0.41) | CYP1A2MAPK1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL17401259 | 0.82 | DGKA (0.67) | ALDH1A1DGKALMNATSHRPAM | |
| SCHEMBL17401261 | 0.82 | DGKA (0.67) | ALDH1A1DGKALMNATSHRPAM | |
| SCHEMBL11628693 | 0.82 | DGKA (0.67) | ALDH1A1DGKALMNATSHRPAM | |
| SCHEMBL11593236 | 0.81 | CYP1A2 (0.53) | CYP1A2MAPK1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL31618323 | 0.80 | CYP1A2 (0.56) | CYP1A2MAPK1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL536437 | 0.80 | DGKA (0.60) | ALDH1A1DGKALMNATSHRNFKB1 | |
| SCHEMBL16312536 | 0.78 | DGKA (0.56) | ALDH1A1DGKALMNAPAML3MBTL1 | |
| SCHEMBL4401743 | 0.78 | DGKA (0.64) | ALDH1A1DGKALMNATSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003089476-A1 | CROSS-LINKED HYALURONATE COMPOUNDS | GENZYME CORPORATION (US) | 2003-10-30 | — | — | WO | disclosed |