SCHEMBL7098692

SCHEMBL7098692

COC(=O)[C@H](Cc1ccc(NC(=O)c2c(Cl)cc(Cl)cc2Cl)cc1)NC(=O)C1CCC(C)(C(=O)O)C1(C)C

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ITGB1 P05556 17/20 0.47
ITGA4 P13612 17/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7098694 1.00 ITGB1 (0.47) ITGB1ITGA4MEN1KMT2ANPSR1
SCHEMBL7098054 0.93 ITGB1 (0.54) ITGB1ITGA4
SCHEMBL7103697 0.93 ITGB1 (0.54) ITGB1ITGA4
SCHEMBL7102026 0.92 ITGB1 (0.54) ITGB1ITGA4
SCHEMBL7105450 0.92 ITGB1 (0.54) ITGB1ITGA4
SCHEMBL7105443 0.90 ITGB1 (0.43) ITGB1ITGA4
SCHEMBL7105442 0.90 ITGB1 (0.43) ITGB1ITGA4
SCHEMBL7098706 0.88 MEN1 (0.45) ITGB1ITGA4MEN1KMT2ANPSR1
SCHEMBL7098708 0.88 MEN1 (0.45) ITGB1ITGA4MEN1KMT2ANPSR1
SCHEMBL7103896 0.88 ITGB1 (0.56) ITGB1ITGA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0991619-B1 INHIBITORS OF ALPHA 4-BETA 1 MEDIATED CELL ADHESION TANABE SEIYAKU CO (JP) 2003-09-10 EP claimed