Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 3/20 | 0.40 |
| ▸ | PSMA7 | O14818 | 3/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.40 |
| ▸ | PSMA1 | P25786 | 3/20 | 0.40 |
| ▸ | PSMA2 | P25787 | 3/20 | 0.40 |
| ▸ | PSMA3 | P25788 | 3/20 | 0.40 |
| ▸ | PSMA4 | P25789 | 3/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.40 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.40 |
| ▸ | PSMA5 | P28066 | 3/20 | 0.40 |
| ▸ | PSMB4 | P28070 | 3/20 | 0.40 |
| ▸ | PSMB6 | P28072 | 3/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098706 | 1.00 | MEN1 (0.45) | MEN1KMT2ANPSR1TAS1R3TAS1R1 | |
| SCHEMBL7102565 | 0.93 | ITGB1 (0.48) | MEN1KMT2ANPSR1ITGB1ITGA4 | |
| SCHEMBL7102563 | 0.93 | ITGB1 (0.48) | MEN1KMT2ANPSR1ITGB1ITGA4 | |
| SCHEMBL7098016 | 0.90 | TAS1R3 (0.39) | MEN1KMT2ANPSR1TAS1R3TAS1R1 | |
| SCHEMBL7098020 | 0.90 | TAS1R3 (0.39) | MEN1KMT2ANPSR1TAS1R3TAS1R1 | |
| SCHEMBL7098043 | 0.90 | ITGB1 (0.51) | MEN1KMT2ANPSR1ITGB1ITGA4 | |
| SCHEMBL7098046 | 0.90 | ITGB1 (0.51) | MEN1KMT2ANPSR1ITGB1ITGA4 | |
| SCHEMBL7098692 | 0.88 | ITGB1 (0.47) | MEN1KMT2ANPSR1ITGB1ITGA4 | |
| SCHEMBL7098694 | 0.88 | ITGB1 (0.47) | MEN1KMT2ANPSR1ITGB1ITGA4 | |
| SCHEMBL7105446 | 0.88 | MEN1 (0.46) | MEN1KMT2ANPSR1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991619-B1 | INHIBITORS OF ALPHA 4-BETA 1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2003-09-10 | — | — | EP | claimed |