Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 13/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 12/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098766 | 1.00 | ITGA4 (0.55) | ITGA4NPSR1MEN1KMT2AITGB1 | |
| SCHEMBL7098189 | 0.88 | ITGA4 (0.49) | ITGA4NPSR1MEN1KMT2AITGB1 | |
| SCHEMBL7516096 | 0.88 | ITGA4 (0.49) | ITGA4NPSR1MEN1KMT2AITGB1 | |
| SCHEMBL7098193 | 0.88 | ITGA4 (0.49) | ITGA4NPSR1MEN1KMT2AITGB1 | |
| SCHEMBL7100744 | 0.88 | ITGA4 (0.51) | ITGA4NPSR1MEN1KMT2AITGB1 | |
| SCHEMBL7100747 | 0.88 | ITGA4 (0.51) | ITGA4NPSR1MEN1KMT2AITGB1 | |
| SCHEMBL7101134 | 0.86 | ITGB1 (0.50) | ITGA4ITGB1 | |
| SCHEMBL7101131 | 0.86 | ITGB1 (0.50) | ITGA4ITGB1 | |
| SCHEMBL7099187 | 0.86 | ITGA4 (0.49) | ITGA4NPSR1MEN1KMT2AITGB1 | |
| SCHEMBL7099189 | 0.86 | ITGA4 (0.49) | ITGA4NPSR1MEN1KMT2AITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991619-B1 | INHIBITORS OF ALPHA 4-BETA 1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2003-09-10 | — | — | EP | claimed |